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KMID : 0338419960110020157
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Korean Journal of Internal Medicine
1996 Volume.11 No. 2 p.157 ~ p.160
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Complete resolution of airway hyperresponsiveness in aspirin-sensitive asthmatic patients
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박해심:Park Hae-Sim
저자없음:No authors listed/저자없음:No authors listed
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Abstract
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Appreciable numbers of aspirin-sensitive asthmatic patients have chronic steroid-dependent severe asthmatic symptoms. We report four cases of aspirin-sensitive asthmatics who had mild to severe asthmatic symptoms, whose methacholine PC20 level ranged from 0.6 to 22 mg/ml at the first visit. The aspirin sensitivity was confirmed by lysine-aspirin bronchoprovocation. After anti-asthmatic medications and avoidance of salicylate-containing agents, airway hyperresponsiveness and respiratory symptoms disappeared for two to 30 months. These results suggest that early detection and careful avoidance of salicylate-containing agents may have a beneficial effect resulting in the resolution of airway hyperresponsiveness in aspirin-sensitive asthmatic patients.
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KEYWORD
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Aspirin-sensitive asthma, Disappearance of airway hyperresponsiveness
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